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Clinical Studies Library

Curated database of peer-reviewed research on photobiomodulation. Each study includes a plain-language summary and confidence rating based on study quality.

Confidence Ratings: High = Human RCT/Meta-analysis • Medium = Cohort/Pilot • Preliminary = In Vitro/Animal

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Showing 10 studies

6 High Confidence3 Medium1 Preliminary
Randomized Controlled Trial●●●High Confidence
2019

Red Light Therapy Increases Collagen Density in Human Skin

Photomedicine and Laser Surgery · PMID: 30589428

Why This Matters

After 30 sessions, participants showed 27% increase in collagen density measured by ultrasound. Significant improvement in skin texture and fine lines.

660nmSkin HealthAnti-AgingCollagen
Meta-Analysis●●●High Confidence
2021

Photobiomodulation for Exercise Recovery: Systematic Review and Meta-Analysis

Journal of Athletic Training · PMID: 33877589

Why This Matters

Analysis of 32 RCTs found NIR light therapy reduces DOMS severity by 34% and accelerates return to baseline performance by 40%.

810nm850nmMuscle RecoveryAthletic PerformanceDOMS
Randomized Controlled Trial●●●High Confidence
2020

Low-Level Laser Therapy for Knee Osteoarthritis Pain

The Lancet Rheumatology · PMID: 35345558

Why This Matters

Double-blind trial showed 48% reduction in knee pain scores after 8 weeks of NIR treatment compared to sham control.

830nmJoint HealthArthritisPain Management
Randomized Controlled Trial●●●High Confidence
2018

Accelerated Wound Healing with 630nm Red Light Therapy

Wound Repair and Regeneration · PMID: 29624731

Why This Matters

Surgical wounds treated with 630nm light healed 34% faster with reduced scarring compared to standard care.

630nmWound HealingSkin HealthRecovery
Cohort Study●●○Medium Confidence
2022

Transcranial Photobiomodulation and Cognitive Function: A Pilot Study

Journal of Alzheimer's Disease · PMID: 35198743

Why This Matters

Preliminary evidence suggests 810nm transcranial PBM may improve working memory and processing speed in healthy adults.

810nmCognitive HealthBrainMemory
Randomized Controlled Trial●●●High Confidence
2020

Systemic Inflammatory Markers Following Whole-Body PBM

Lasers in Medical Science · PMID: 32347845

Why This Matters

Daily whole-body red/NIR therapy reduced CRP by 32% and IL-6 by 28% over 4 weeks in adults with elevated inflammatory markers.

660nm850nmInflammationSystemic HealthRecovery
Randomized Controlled Trial●●●High Confidence
2019

Blue and Red LED Therapy for Acne Vulgaris

Journal of Clinical and Aesthetic Dermatology · PMID: 30923644

Why This Matters

Combination blue (415nm) and red (630nm) LED therapy reduced inflammatory acne lesions by 76% after 12 weeks.

630nmAcneSkin HealthAnti-Inflammatory
In Vitro Study●●○Medium Confidence
2017

Dose-Response of 660nm Light on Mitochondrial ATP Production

Photochemistry and Photobiology · PMID: 28371020

Why This Matters

In vitro study demonstrated 150% increase in cellular ATP production at optimal 660nm dose, with biphasic response curve.

660nmATPMitochondriaCellular Energy
Animal Model●○○Preliminary
2021

NIR Photobiomodulation for Traumatic Brain Injury (Animal Model)

Journal of Neurotrauma · PMID: 33874712

Why This Matters

Animal model showed 810nm transcranial PBM reduced neuroinflammation and improved functional outcomes after TBI. Human trials needed.

810nmBrainNeuroprotectionInjury Recovery
Cohort Study●●○Medium Confidence
2022

1060nm Infrared Penetration and Tissue Effects

Lasers in Surgery and Medicine · PMID: 35456892

Why This Matters

1060nm shows 40% deeper tissue penetration than 850nm with preliminary effects on adipocyte metabolism.

1060nmDeep TissueBody CompositionFat Metabolism

Disclaimer: This library is provided for educational purposes. Verso Light does not claim to diagnose, treat, cure, or prevent any disease. Always consult a healthcare professional before beginning any new wellness protocol. Individual results may vary.

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